Next generation memory, mood and cognitive booster to help you think fast, fast.*

Rated 4.4 out of 5 stars
82 Reviews
Subscribe: 180 day supply
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Subscribe: 90 day supply
  • Ships every 90 days
  • Free shipping in the US
  • Cancel anytime
One time purchase
Nootropic for focus and sustained energy. Improve attention and alertness on day 1*† 
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every 180 days
sleep support+
The deep and restorative sleep you've always dreamt about*
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every 180 days
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improve memory enhance mental processing speed combat brain fog
Key ingredients
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Cognizin® Kanna Resveratrol
  • GMO-free
  • gluten-free
  • dairy-free
  • soy-free
  • vegan
  • third-party tested
Supplement Facts
Serving Size: 2 capsules
Servings Per Container: 30
Amount Per Serving


500 mg

Trans-resveratrol from Saccharomyces cerevisiae (as Verti-te™)

150 mg

Sceletium tortuosum extract (aerial parts) (as Zembrin®)

25 mg
*Daily Value (DV) not established
The science-backed secret to brain longevity & performance*
improve learning, memory, & cognitive performance*

Robust clinical trials show taking this compound is good for memory and learning. What’s more, brain guard+ includes the ideal dose of a patented form called Cognizin® — which is clinically shown to*†

  • Improve processing speed on day 1
  • Enhance attention span & mental clarity in 4 weeks
  • Increase mental energy in 6 weeks
  • Improve memory performance in 12 weeks**
support executive function & cognitive flexibility*

Kanna is actually a succulent that has calming benefits. Zembrin®, the patented form of plant-derived extract, is in brain guard+ at the science-backed dose of 25 milligrams. Perks include:*†

  • Enhance stress resilience on day 1
  • Reduce emotional reactivity on day 1
  • Improve cognitive flexibility (the ability to think quickly between different tasks) in 3 weeks
enhance brain blood flow & mental processing speed*

This renowned longevity antioxidant also boasts notable benefits for your brain. We use a branded form of the ingredient (Veri-te™), and supplementing with resveratrol can help:*

  • Enhance processing speed
  • Sharpen verbal memory
  • Increase blood flow to the brain (which efficiently delivers the nutrients & oxygen this vital organ needs to function)
Supported by Clinical Research

Expert Reviews

Neuronutrients in brain guard+ are working hard for your brain*

Ilene Ruhoy, M.D., Ph.D.
Board-Certified Neurologist & Environmental Toxicologist

Cognizin® has impressive efficacy to nourish and promote our brain and executive function.*

Eri Nakazaki, Ph.D.
Lead R&D Researcher, Kirin Central Research Institute

Unique trio of neuroprotective ingredients with clinical research demonstrating effectiveness*

Uma Naidoo, M.D.
Nutritional Psychiatrist, Professional Chef, & Bestselling Author

This formula is remarkably effective for brain protection.*

Ella Davar, R.D., CDN
Longevity Dietitian & Health Counselor

Clinically efficacious formula targeting neuroprotection and healthy cognitive aging*

Milene Brownlow, Ph.D.
Neuroscientist & Cognitive Health Scientist

Elevates executive function and enhances cognitive flexibility*

Jeremy Appleton, N.D.
Director, PLT Scientific & Medical Affairs

brain guard+ has greatly improved my cognitive performance and ability to cut through stress.*

India Edwards
mbg Editor

Take 2 capsules daily with water (in the morning but also safe for nighttime use) to start seeing the benefits of brain guard+ over time.

Week 1+: Improve working memory, processing speed, stress response & increase sense of calm*†
Week 3+: Improve cognitive resilience, flexibility & agility*†
Week 4+: Enhance attention span & mental clarity*†
Week 6+: Increase brain energy reserves (by 14%)*†
Week 12+: Improve overall memory*†
Week 14+: Improve blood flow to the brain*†

Customer Reviews

What customers are saying about brain guard+ *
Rated 4.4 out of 5 stars
Based on 82 reviews
Total 5 star reviews: 61 Total 4 star reviews: 5 Total 3 star reviews: 7 Total 2 star reviews: 4 Total 1 star reviews: 5
80%would recommend this product
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82 reviews
  • Donna S.
    Verified Reviewer
    I recommend this product
    Wellness Concern: Mental processing speed, Brain fog, Focus
    Age: 55-64
    Gender: Female
    Usage: 1-3 months
    Rated 5 out of 5 stars
    Brain guard

    It did help with my mental cognition and recollection. Have recommended it to others!!

  • Mary R.
    Verified Buyer
    I recommend this product
    Wellness Concern: Memory and recall
    Age: 65-74
    Gender: Male
    Usage: 3-6 months
    Rated 5 out of 5 stars
    A Clearer Mind

    That recalls better, is more alert and active!

  • Dorrice B.
    Verified Buyer
    I recommend this product
    Wellness Concern: Focus, Memory and recall
    Rated 5 out of 5 stars
    Great Product

    I've been taking brain guard for two months and I am very pleased with this product. Definitely seems to be making a difference.

  • Eva F.
    Verified Buyer
    I recommend this product
    Wellness Concern: Memory and recall
    Age: 75+
    Gender: Female
    Usage: Less than 1 month
    Rated 5 out of 5 stars
    Brain Supplements

    It makes a difference in remembering

  • Troy R.
    Verified Buyer
    I recommend this product
    Wellness Concern: Memory and recall, Mental processing speed, Brain fog, Focus, Attention
    Age: 55-64
    Gender: Male
    Usage: 1-3 months
    Rated 5 out of 5 stars
    Brain Guard

    Been taking Brain Guard supplement for 10 weeks and feeling cognitive abilities increasing with removing work details and loving my wife and being able to communicating correctly with loving words ! Absolutely trust Dr. Caroline Leaf and her recommendation!

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Frequently Asked Questions
Email us at  [email protected]  or visit our  Help Center.

How should I take brain guard+?

What time of day should I take brain guard+?

Why would I need or consider a targeted brain support supplement?

What is a nootropic?

Can you take brain guard+ and focus+ at the same time?

Does mindbodygreen offer a refillable program?

Is brain guard+ vegan?

†Benefits assume daily use and are evidence-based estimates rooted in clinical science at the ingredient level. Individual results may vary.

ultimate multivitamin+

daily essentials
Daily comprehensive multi that provides your body with a steady supply of the nutrients it needs to function at its best*

brain guard+

Brain nutrition for cognitive performance and mental clarity*


gut health
Four targeted strains to beat bloating and support gut health*

omega-3 potency+

daily essentials
Delivers the right amount of crucial fatty acids so your body can function at its best.*


muscle health
Next-generation support for muscle & brain health*

grass-fed whey protein isolate+

muscle health
25 grams of clean protein to support lean muscle mass*

muscle health bundle+

muscle health
The perfect duo to build lean muscle and maintain a healthy body composition*

eye health+

Daily Essentials
Visual performance support for the digital age*


metabolic health
Multi-pronged approach to promote healthy weight & body composition*

sleep support+

Finally, a supplement that delivers deep sleep - without any morning grogginess*

postbiotic hand wash

barrier supporting skin care
Bright scent, lush lather & hydrating ingredients

postbiotic hand cream

microbiome skin care
Rich yet fast-absorbing formula that nourish your microbiome

dry body oil

barrier supporting skin care
Instantly restore radiance to dull, lackluster skin

organic fiber potency+

gut health
Advanced fiber sources to promote satiety and regularity*

beauty & gut collagen+

The one-step beauty routine for holistic inside-out support.*

best skin+

A revolutionary, science-backed cosmeceutical*

vitamin D3 potency+

daily essentials
Optimized vitamin D3 with absorption technology for whole-body health*


Sustained daily energy and focus, minus the crash*

liver detox+

daily essentials
Detox support to promote liver and whole-body cleanup*

dream mist

nighttime linen mist
A turn-down service for your senses

turmeric potency+

Daily Essentials
Promotes a healthy inflammatory response for whole-body health*

postbiotic body lotion

barrier supporting skin care
Ultra-hydrating formula that nourishes your skin barrier

vitamin C potency+

Daily Essentials
A potent antioxidant that helps your body run properly every single day— not just certain times of the year.*

gut health bundle+

Gut Health
Reset your gut microbiome and optimize digestive health through the power of pre- and probiotics*

methylation support+

daily essentials
Supports cardiovascular health with ultra potent B vitamin complex*

organic greens detox+

daily essentials
Nutritional power of daily greens made easy*

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