with citicoline, kanna, and resveratrol
Most people don’t realize our brains start shrinking in our 30’s. It’s never too early to get a head start on brain health with this neurologist-recommended supplement.* Take brain guard+ to feel sharper, clearer, and calmer, all at the same time.*
- Improve working memory on day 1*†
- Improve stress response on day 1*†
- Improve processing speed on day 1*†
- Combat brain fog and enhance mental clarity and attention span*
Our cutting-edge formula supports neurotransmitter production and increases blood flow to the brain to help enhance mental sharpness. This trio of clinically-researched nootropics – 2 patented and 1 proprietary – are designed to improve how your brain works and promote brain longevity.*
- Promotes memory creation, recall, and retention*
- Supports blood flow to the brain*
- Improves learning and processing speed*
- Elevates executive function, cognitive flexibility, and performance*
- Combats occasional brain fog and promotes mental clarity*
Take two (2) capsules daily with water or as recommended by your health care practitioner. If pregnant, consult your health care practitioner before using this product. Keep out of reach of children.
CITICOLINE
Our citicoline (as Cognizin®) is a powerhouse neuronutrient. Across the lifespan, citicoline is critical for neurotransmitter production and neuronal health and function. Featured in its full-potency dose to benefit learning, memory, and cognitive performance, citicoline has also been clinically shown to increase mental ATP energy, brain cell membrane formation (phospholipids), mental processing speed, and ability to tune out distractions.*
500 mg
KANNA
A nootropic botanical, our Zembrin® kanna (Sceletium tortuosum) extract is sustainably sourced from South Africa. With millennia of use, this indigenous plant helps balance key neurotransmitters (e.g., serotonin) and brain waves. Zembrin® is also clinically shown to improve executive function and cognitive flexibility, while enhancing mental well-being and mood by strengthening our resilience to stressful stimuli and supporting a sense of serenity.*
25 mg
RESVERATROL
Key phytonutrients are neuroprotective. Our fermentation-derived resveratrol delivers antioxidant and anti-inflammatory actions to combat oxidative stress and foster cellular resilience, mitochondrial health, and longevity. This polyphenol’s unique nitric oxide-mediated vasoactive properties and cerebrovascular benefits are clinically shown to increase blood flow to the brain and enhance processing speed, verbal memory, and cognitive task performance.*
150 mg
Inside brain guard+
Our citicoline (as Cognizin®) is a powerhouse neuronutrient. Across the lifespan, citicoline is critical for neurotransmitter production and neuronal health and function. Featured in its full-potency dose to benefit learning, memory, and cognitive performance, citicoline has also been clinically shown to increase mental ATP energy, brain cell membrane formation (phospholipids), mental processing speed, and ability to tune out distractions.*
A nootropic botanical, our Zembrin® kanna (Sceletium tortuosum) extract is sustainably sourced from South Africa. With millennia of use, this indigenous plant helps balance key neurotransmitters (e.g., serotonin) and brain waves. Zembrin® is also clinically shown to improve executive function and cognitive flexibility, while enhancing mental well-being and mood by strengthening our resilience to stressful stimuli and supporting a sense of serenity.*
Key phytonutrients are neuroprotective. Our fermentation-derived resveratrol delivers potent antioxidant actions to combat oxidative stress and foster cellular resilience, mitochondrial health, and longevity. This polyphenol’s unique nitric oxide-mediated vasoactive properties and cerebrovascular benefits are clinically shown to increase blood flow to the brain and enhance processing speed, verbal memory, and cognitive task performance.*
What we leave out is just as important as what we add in
Got Questions?
How should I take brain guard+?
Take 2 capsules daily with water or as recommended by your health care practitioner. Store tightly sealed in a cool, dry place without direct sunlight. If you are pregnant or breastfeeding or planning to become pregnant, out of an abundance of caution, we recommend consulting your health care practitioner before using brain guard+ or any dietary supplement product. Keep out of reach of children.
What time of day should I take brain guard+?
While that decision is completely up to you, many customers choose to take brain guard+ in the morning or midday to take full advantage of this nootropic supplement's multidimensional brain power benefits (i.e., mental clarity, learning, processing, memory, cognitive performance, mood balance, and more). Since brain guard+ does not deliver stimulating effects, it can be combined with your coffee ritual or other caffeine-containing foods, beverages, and supplements (e.g., mbg's focus+ supplement). There is no evidence that brain guard+ ingredients will disrupt sleep. Every individual is unique, so we recommend you personalize your brain guard+ routine to best suit your needs and goals.*
Why would I need or consider a targeted brain support supplement?
Conversations of adult brain health and cognitive function used to be reserved mostly for “older” years of life, but not anymore. As it turns out, it’s never too early to be proactive about protecting and nourishing your brain. Whether you’re 25 or 75, the scientific discovery of a diverse array of nootropic compounds and advent of neurohacking have changed the brain game, if you will. Our breakthrough brain guard+ supplement provides proactive brain health support across the adult lifespan—optimizing your cognitive longevity, or “brain span.”*
mbg’s brain guard+ features a trio of neuroprotective ingredients providing comprehensive and multidimensional cognitive health and function support. Nutrient-bioactive citicoline (Cognizin®), not only promotes healthy cell membranes and protection of neural structures but also supports memory, mental sharpness and recall, learning, mental energy, and ability to tune out distractions, to name a few. Unique botanical Sceletium tortuosum (Zembrin®) (commonly known as kanna) promotes cognitive and emotional processes including executive function, cognitive flexibility, and mood balance and relaxation. Finally, longevity polyphenolic phytonutrient resveratrol (Veri-te™) with its antioxidant and vasoactive actions enhances brain blood flow, supports vascular brain health, verbal memory, and cognitive task performance.*
This powerhouse active ingredient trio is delivered in full-potency, clinically researched doses to provide neuroprotective brain nutrition and cognitive vitality advantage each day, whether you are looking to support memory and cognitive performance or be proactive and on top of your brain health, your bases will be covered.*
What is a nootropic?
Our brain guard+ dietary supplement is a "nootropic," a scientific term that refers to a nutrient, botanical phytonutrient, bioactive, or combination of those ingredients that has the ability to act in helpful ways in the central nervous system (CNS), specifically the brain—to promote the health of the brain and enhance its functions. In layman's terms, nootropic actions confer "brain power" in the broadest sense. More specifically, this could look like mental clarity and sharpness, memory, neuronal function, neurotransmitter balance, cognitive performance, and more.*
Can you take brain guard+ and focus+ at the same time?
Absolutely! The same person who leverages brain guard+ may also want to incorporate our focus+ supplement daily, too. No worries, we created the entire mindbodygreen supplements+ portfolio with this synergy potential in mind.
Our focus+ supplement delivers clean, sustainable mind-body energy and focus that you can literally feel, whether you’re working, working out, or running errands. With instant- and sustained-release plant-origin caffeine (from the whole coffee fruit and green coffee beans), L-theanine, ginseng, guarana, and vitamin B12, focus+ delivers sustained energy and focus for enhanced performance and productivity. With advanced technology for extended-time release, this unique nootropic formula delivers on its promise to provide focused energy minus the caffeine crash (goodbye, afternoon slump).*
Meanwhile, our complementary brain guard+ is a nootropic supplement that leverages a trio of neuroprotective bioactives supporting multiple dimensions of daily cognitive health and function including learning, memory, and mental clarity (to name a few), while also providing necessary nourishment for the brain on a daily basis, including supporting the health of neuronal structures, promoting blood flow to the brain, and providing antioxidant protection.*
In summary, our two powerhouse nootropic formulas (focus+ and brain guard+) are complementary and intentionally unique in their ingredients and brain-support actions. You will find both products in our nootropic collection.*
Does mindbodygreen offer a refillable program?
Our high-quality formulas are delivered in premium, sustainable, and recyclable packaging (recyclable amber glass bottles and jars, recyclable bags, and recyclable cardboard shipping boxes made from 100% recycled paper). Always looking towards the latest innovations, we carefully and intentionally source our eco-friendly packaging to prioritize the environment, but also to protect the premium ingredients in our capsules, gelcaps, and powders (i.e., vitamins, minerals, botanicals, peptides, probiotics, bioactives) from UV light degradation. This is pivotal to ensure quality standards throughout the lifecycle of the product.
Unfortunately many refillable bags or containers do not provide the same protection and stability for our ingredients as our amber glass (bottles, jars) and PET bags achieve. What's more, the product-specific manufacturing information (i.e., specific identifiers such as the lot and date) stamped on each product would be lost when the customer discards the refill packaging, as is customary. That lost information would not enable us to comply with a variety of very important FDA regulations specific to dietary supplements (e.g., cGMPs, adverse event reporting, etc.), and regulatory compliance is something that mindbodygreen respects and prioritizes. From an additional safety standpoint, there are also microbial contamination concerns with refillable vessels over time. Thank you for your consideration as to why we have thoughtfully curated our packaging in the way we do.
Is brain guard+ vegan?
Yes. This vegan product is also GMO-free, gluten-free, soy-free, dairy-free, and major food allergen free.
Customer Reviews
What real people are saying about brain guard+
Best Sellers
What sets us apart
4 Rounds of testing
Certified lab
Pure ingredients
with citicoline, kanna, and resveratrol
Most people don’t realize our brains start shrinking in our 30’s. It’s never too early to get a head start on brain health with this neurologist-recommended supplement.* Take brain guard+ to feel sharper, clearer, and calmer, all at the same time.*
- Improve working memory on day 1*†
- Improve stress response on day 1*†
- Improve processing speed on day 1*†
- Combat brain fog and enhance mental clarity and attention span*
Our cutting-edge formula supports neurotransmitter production and increases blood flow to the brain to help enhance mental sharpness. This trio of clinically-researched nootropics – 2 patented and 1 proprietary – are designed to improve how your brain works and promote brain longevity.*
Most people don’t realize our brains start shrinking in our 30’s. It’s never too early to get a head start on brain health with this neurologist-recommended supplement.* Take brain guard+ to feel sharper, clearer, and calmer, all at the same time.*
- Improve working memory on day 1*†
- Improve stress response on day 1*†
- Improve processing speed on day 1*†
- Combat brain fog and enhance mental clarity and attention span*
Our cutting-edge formula supports neurotransmitter production and increases blood flow to the brain to help enhance mental sharpness. This trio of clinically-researched nootropics – 2 patented and 1 proprietary – are designed to improve how your brain works and promote brain longevity.*
- Promotes memory creation, recall, and retention*
- Supports blood flow to the brain*
- Improves learning and processing speed*
- Elevates executive function, cognitive flexibility, and performance*
- Combats occasional brain fog and promotes mental clarity*
Take two (2) capsules daily with water or as recommended by your health care practitioner. If pregnant, consult your health care practitioner before using this product. Keep out of reach of children.
CITICOLINE
Our citicoline (as Cognizin®) is a powerhouse neuronutrient. Across the lifespan, citicoline is critical for neurotransmitter production and neuronal health and function. Featured in its full-potency dose to benefit learning, memory, and cognitive performance, citicoline has also been clinically shown to increase mental ATP energy, brain cell membrane formation (phospholipids), mental processing speed, and ability to tune out distractions.*
500 mg
KANNA
A nootropic botanical, our Zembrin® kanna (Sceletium tortuosum) extract is sustainably sourced from South Africa. With millennia of use, this indigenous plant helps balance key neurotransmitters (e.g., serotonin) and brain waves. Zembrin® is also clinically shown to improve executive function and cognitive flexibility, while enhancing mental well-being and mood by strengthening our resilience to stressful stimuli and supporting a sense of serenity.*
25 mg
RESVERATROL
Key phytonutrients are neuroprotective. Our fermentation-derived resveratrol delivers antioxidant and anti-inflammatory actions to combat oxidative stress and foster cellular resilience, mitochondrial health, and longevity. This polyphenol’s unique nitric oxide-mediated vasoactive properties and cerebrovascular benefits are clinically shown to increase blood flow to the brain and enhance processing speed, verbal memory, and cognitive task performance.*
150 mg
- Free US shipping on all subscriptions or orders valuing $98 and up
- Cancel subscriptions, anytime
- Each bottle contains a 30-day supply
- 30-day money back guarantee
- Formulated, manufactured, and packaged in the USA
-
GMO-free
-
gluten-free
-
dairy-free
-
soy-free
-
vegan
-
major food allergen free
-
GMO-free
-
gluten-free
-
dairy-free
-
soy-free
-
vegan
-
major food allergen free

Sustained daily energy and focus, minus the crash*

Sustained daily energy and focus, minus the crash*
Our brain guard+ formula

Our citicoline (as Cognizin®) is a powerhouse neuronutrient. Across the lifespan, citicoline is critical for neurotransmitter production and neuronal health and function. Featured in its full-potency dose to benefit learning, memory, and cognitive performance, citicoline has also been clinically shown to increase mental ATP energy, brain cell membrane formation (phospholipids), mental processing speed, and ability to tune out distractions.*
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A nootropic botanical, our Zembrin® kanna (Sceletium tortuosum) extract is sustainably sourced from South Africa. With millennia of use, this indigenous plant helps balance key neurotransmitters (e.g., serotonin) and brain waves. Zembrin® is also clinically shown to improve executive function and cognitive flexibility, while enhancing mental well-being and mood by strengthening our resilience to stressful stimuli and supporting a sense of serenity.*

Key phytonutrients are neuroprotective. Our fermentation-derived resveratrol delivers potent antioxidant actions to combat oxidative stress and foster cellular resilience, mitochondrial health, and longevity. This polyphenol’s unique nitric oxide-mediated vasoactive properties and cerebrovascular benefits are clinically shown to increase blood flow to the brain and enhance processing speed, verbal memory, and cognitive task performance.*
Setting higher quality standards
Reviewed by a team of experts
Reviewed by a team of experts
Neuronutrients in brain guard+ are working hard for your brain*
Ilene Ruhoy, M.D., Ph.D.
Clean foods, movement, meditation, and spending time in nature are critical for brain nutrition, regeneration, and longevity. As part of my integrative approach to neurology, I also value smart, holistic formulas that nourish and support brain function and elevate cognitive potential, regardless of stage in life. That's why mbg's brain guard+ excites me. From helping with memory, to supporting executive function, mental clarity, and improving stress resilience—the neuronutrients in brain guard+ are working hard for you and your brain.*
Citicoline has impressive efficacy to nourish and promote our brain and executive function.*
Eri Nakazaki, Ph.D.
As a scientist, I have engaged in many clinical research trials on nutritional bioactives to determine their brain health potential. Leading mbg's brain guard+ formula you'll find the powerhouse neuronutrient citicoline as Cognizin®, which boasts a robust body of published scientific evidence. This nootropic has impressive efficacy to nourish and promote our brain and executive function—supporting the structure and function of our neurons, neurotransmitter levels, and diverse cognitive metrics spanning brain energy, attention, memory, and cognitive performance.*
Unique trio of neuroprotective ingredients with clinical research demonstrating effectiveness*
Uma Naidoo, M.D.
As a doctor and professional chef, my career marries nutritional psychiatry and culinary arts rooted in current nutrition science. So does my life philosophy and approach to health! Merging nutrition and psychiatry, I have a keen interest in targeted ingredients rooted in science that benefit both body and brain. mindbodygreen's brain guard+ embodies this unique intersection with a unique trio of neuroprotective ingredients with clinical research demonstrating their effectiveness across multiple domains of cognitive health, function, and performance.*
This formula is remarkably effective for brain protection.*
Ella Davar, R.D., CDN
When I think of longevity-essential organs in the body, the brain is atop that list. Your brain needs good nutrition. A brain-centric diet with loads of plants, healthy fats like omega-3s, and quality protein is essential. But to even further enhance cognitive vitality with targeted nutrients and phytonutrients, I recommend brain guard+. With citicoline for attention and memory, kanna for cognitive flexibility and calm, and resveratrol for cerebral blood flow and antioxidant support—this formula is remarkably effective for brain protection.*
Clinically efficacious formula targeting neuroprotection and healthy cognitive aging*
Milene Brownlow, Ph.D.
Preserving cognitive health throughout our lifetime is a key component to overall wellness, and the earlier the better. This brain guard+ formula by mindbodygreen combines three powerful, science-rooted bioactives (citicoline, kanna, and resveratrol) to support multiple domains of cognitive and mental health. After all, who doesn't want to maintain or even improve their brain health? I find that with our busy schedules and overstimulated minds, we can all benefit from clinically efficacious formulas targeting neuroprotection and healthy cognitive aging!*
Elevates executive function and enhances cognitive flexibility*
Jeremy Appleton, N.D.
Evidence-based botanicals with nootropic actions are one of my specialties as a naturopathic healthcare practitioner. One of the most exciting botanicals in the cognitive arena is the South African succulent Sceletium tortuosum (aka kanna). Featured in brain guard+, this clinically researched and patented Zembrin® extract promotes mental agility and calm, at the same time. Through its impact on serotonin levels, brain waves, and neurocircuitry—this unique plant extract helps reduce reactivity to stress, elevates executive function, and enhances cognitive flexibility.*
brain guard+ has greatly improved my cognitive performance and ability to cut through stress.*
India Edwards
As a full-time editor juggling graduate school and a small business, my brain is constantly taking in information, and I often find myself battling brain fog by the afternoon. Even though I'm still in my early 20s, I want to protect, preserve, and even sharpen my cognitive function and be a lifelong learner! Enter brain guard+. Adding this clean and research-backed formula to my daily routine has greatly improved my cognitive performance and ability to cut through stress. It makes me feel aligned and able to tackle a full day of productivity (minus the afternoon fog).*
Customer Reviews
Learn About Our Ingredients
Frequently Asked Questions
How should I take brain guard+?
Take 2 capsules daily with water or as recommended by your health care practitioner. Store tightly sealed in a cool, dry place without direct sunlight. If you are pregnant or breastfeeding or planning to become pregnant, out of an abundance of caution, we recommend consulting your health care practitioner before using brain guard+ or any dietary supplement product. Keep out of reach of children.
What time of day should I take brain guard+?
While that decision is completely up to you, many customers choose to take brain guard+ in the morning or midday to take full advantage of this nootropic supplement's multidimensional brain power benefits (i.e., mental clarity, learning, processing, memory, cognitive performance, mood balance, and more). Since brain guard+ does not deliver stimulating effects, it can be combined with your coffee ritual or other caffeine-containing foods, beverages, and supplements (e.g., mbg's focus+ supplement). There is no evidence that brain guard+ ingredients will disrupt sleep. Every individual is unique, so we recommend you personalize your brain guard+ routine to best suit your needs and goals.*
Why would I need or consider a targeted brain support supplement?
Conversations of adult brain health and cognitive function used to be reserved mostly for “older” years of life, but not anymore. As it turns out, it’s never too early to be proactive about protecting and nourishing your brain. Whether you’re 25 or 75, the scientific discovery of a diverse array of nootropic compounds and advent of neurohacking have changed the brain game, if you will. Our breakthrough brain guard+ supplement provides proactive brain health support across the adult lifespan—optimizing your cognitive longevity, or “brain span.”*
mbg’s brain guard+ features a trio of neuroprotective ingredients providing comprehensive and multidimensional cognitive health and function support. Nutrient-bioactive citicoline (Cognizin®), not only promotes healthy cell membranes and protection of neural structures but also supports memory, mental sharpness and recall, learning, mental energy, and ability to tune out distractions, to name a few. Unique botanical Sceletium tortuosum (Zembrin®) (commonly known as kanna) promotes cognitive and emotional processes including executive function, cognitive flexibility, and mood balance and relaxation. Finally, longevity polyphenolic phytonutrient resveratrol (Veri-te™) with its antioxidant and vasoactive actions enhances brain blood flow, supports vascular brain health, verbal memory, and cognitive task performance.*
This powerhouse active ingredient trio is delivered in full-potency, clinically researched doses to provide neuroprotective brain nutrition and cognitive vitality advantage each day, whether you are looking to support memory and cognitive performance or be proactive and on top of your brain health, your bases will be covered.*
What is a nootropic?
Our brain guard+ dietary supplement is a "nootropic," a scientific term that refers to a nutrient, botanical phytonutrient, bioactive, or combination of those ingredients that has the ability to act in helpful ways in the central nervous system (CNS), specifically the brain—to promote the health of the brain and enhance its functions. In layman's terms, nootropic actions confer "brain power" in the broadest sense. More specifically, this could look like mental clarity and sharpness, memory, neuronal function, neurotransmitter balance, cognitive performance, and more.*
Can you take brain guard+ and focus+ at the same time?
Absolutely! The same person who leverages brain guard+ may also want to incorporate our focus+ supplement daily, too. No worries, we created the entire mindbodygreen supplements+ portfolio with this synergy potential in mind.
Our focus+ supplement delivers clean, sustainable mind-body energy and focus that you can literally feel, whether you’re working, working out, or running errands. With instant- and sustained-release plant-origin caffeine (from the whole coffee fruit and green coffee beans), L-theanine, ginseng, guarana, and vitamin B12, focus+ delivers sustained energy and focus for enhanced performance and productivity. With advanced technology for extended-time release, this unique nootropic formula delivers on its promise to provide focused energy minus the caffeine crash (goodbye, afternoon slump).*
Meanwhile, our complementary brain guard+ is a nootropic supplement that leverages a trio of neuroprotective bioactives supporting multiple dimensions of daily cognitive health and function including learning, memory, and mental clarity (to name a few), while also providing necessary nourishment for the brain on a daily basis, including supporting the health of neuronal structures, promoting blood flow to the brain, and providing antioxidant protection.*
In summary, our two powerhouse nootropic formulas (focus+ and brain guard+) are complementary and intentionally unique in their ingredients and brain-support actions. You will find both products in our nootropic collection.*
Does mindbodygreen offer a refillable program?
Our high-quality formulas are delivered in premium, sustainable, and recyclable packaging (recyclable amber glass bottles and jars, recyclable bags, and recyclable cardboard shipping boxes made from 100% recycled paper). Always looking towards the latest innovations, we carefully and intentionally source our eco-friendly packaging to prioritize the environment, but also to protect the premium ingredients in our capsules, gelcaps, and powders (i.e., vitamins, minerals, botanicals, peptides, probiotics, bioactives) from UV light degradation. This is pivotal to ensure quality standards throughout the lifecycle of the product.
Unfortunately many refillable bags or containers do not provide the same protection and stability for our ingredients as our amber glass (bottles, jars) and PET bags achieve. What's more, the product-specific manufacturing information (i.e., specific identifiers such as the lot and date) stamped on each product would be lost when the customer discards the refill packaging, as is customary. That lost information would not enable us to comply with a variety of very important FDA regulations specific to dietary supplements (e.g., cGMPs, adverse event reporting, etc.), and regulatory compliance is something that mindbodygreen respects and prioritizes. From an additional safety standpoint, there are also microbial contamination concerns with refillable vessels over time. Thank you for your consideration as to why we have thoughtfully curated our packaging in the way we do.
Is brain guard+ vegan?
Yes. This vegan product is also GMO-free, gluten-free, soy-free, dairy-free, and major food allergen free.
Safety & Quality: Testing Standards

4 rounds of Testing
Our products go through 4 rounds of advanced analytical testing at state-of-the-art labs. Many competitors test only once or twice.

Certified Labs
Our products are tested for precision, potency, and purity, including contaminants like microbes, heavy metals, and pesticides in ISO-certified labs.

Pure Ingredients
None of our products contain artificial coloring or sweeteners, or unnecessary stearates or preservatives.
Ask us anything
Seriously, what’s on your mind?
†Benefits assume daily use and are evidence-based estimates rooted in clinical science at the ingredient level. Individual results may vary.